Flu vaccine may not reduce hospital admission in children

The flu inoculation may not reduce hospital admissions or physician visits in young children, as the vaccine may not match circulating strains of the virus, according to a study.

Researchers in New York studied 414 children under 5 who developed influenza during the winters of 2003-4 or 2004-5 and their vaccination status was compared with over 5000 children who did not catch the flu.

Significant flu vaccine effectiveness was not evident in either of the seasons studied – there was an estimated range of effectiveness from 7-52% in fully vaccinated 6-59 month olds.

The study noted that the strains of the virus used in vaccines were not suitable. For example, in 2003-4 the influenza A virus was responsible for 99% of circulating strains and only 11% of vaccines contained the correct virus.

Authors wrote: 'Further studies of influenza vaccine effectiveness are needed using a variety of study designs to assess the yearly impact of influenza vaccination programmes for children.

Archives of Pediatric Adolescent Medicine (2008): 943-951


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