Propiverine better than oxybutynin for childhood urge incontinence

Children tolerate propiverine better than oxybutynin for treatment of urge incontinence, according to a retrospective observational study conducted by researchers in Germany.

Although propiverine was better tolerated than oxybutynin, both drugs were effective in treating childhood urinary incontinence due to overactive bladder. The researchers identified that treatment periods of at least 2 months were crucial for successful treatment.

The study included 621 children aged 5-14 years. After anticholinergic treatment (437 propiverine, 184 oxybutynin) continence was achieved in 61% and 58% of the patients after 186 and 259 days, respectively. Improvements in voiding frequency were achieved in both treatment groups.

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