Your browser is no longer supported

For the best possible experience using our website we recommend you upgrade to a newer version or another browser.


Your browser appears to have cookies disabled. For the best experience of this website, please enable cookies in your browser

We'll assume we have your consent to use cookies, for example so you won't need to log in each time you visit our site.
Learn more

Gene testing for TN breast cancer sufferers

  • 1 Comment

Women diagnosed with triple-negative (TN) breast cancer should also be offered testing for gene faults which increase their risk of ovarian cancer.

That is according to research published in the British Journal of Cancer, which found women with mutations in the BRCA1 gene have a much higher chance of developing breast cancer but also a greater risk of ovarian cancer.

Consequently researchers, who examined more than 300 women with TN breast cancer, maintain all women under 50 who are diagnosed with the disease should also be offered testing for faults in the BRCA1 gene.

Women with mutations in the gene have up to a 65% chance of developing breast cancer by the time they are 70 and a 40% chance of ovarian cancer.

By testing for faults in the gene hundreds of extra women every year, who may benefit from tailored therapy for BRCA1 breast cancer, could be identified. Women would also be able to tell their families if they have the BRCA1 gene, enabling close relatives to be tested for the hereditary gene.

  • 1 Comment

Readers' comments (1)

  • Targeted screening would be a good thing for women in this group. Preventive post-menopausal laparoscopic oopherectomy could be offered to those in vulnerable groups.

    Unsuitable or offensive? Report this comment

Have your say

You must sign in to make a comment

Please remember that the submission of any material is governed by our Terms and Conditions and by submitting material you confirm your agreement to these Terms and Conditions. Links may be included in your comments but HTML is not permitted.

Related Jobs