Sertraline and mirtazapine do not help patients with Alzheimer's and depression
The antidepressants sertraline and mirtazapine provide no benefit for patients with Alzheimer’s and depression, according to a UK study of 300 patients with both conditions.
The patients were divided into three groups, receiving either sertraline, mirtazapine or a placebo. Decreases in depression symptoms between the groups were no different after 39 weeks.
The authors said the two drugs should be “reconsidered” as first-line treatments for depression in Alzheimer’s.