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Saxagliptin backed for use in Welsh diabetes treatment  

A new drug has been recommended in Wales for use in triple therapy for type 2 diabetes patients.

The DPP-4 inhibitor saxagliptin (Onglyza) has been recommended by the All Wales Medicines Strategy Group for use as part of a triple therapy treatment combination for type 2 diabetes.

Saxagliptin is recommended in NHS Wales for adult type 2 diabetes patients aged 18 years and older, in combination with metformin plus a sulphonylurea when this regimen alone, with diet and exercise, does not provide adequate blood glucose control.

Around 12% of type 2 diabetes patients are currently taking triple therapy regimens, with about 40% of these taking a combination of metformin, a sulphonylurea and a DPP-4 inhibitor.

The strategy group’s recommendation follows a triple therapy licence granted for the product by the European Medicine Agency in January 2013.

The drug is manufactured by Bristol-Myers Squibb and AstraZeneca, which both welcomed the decision.


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