Your browser is no longer supported

For the best possible experience using our website we recommend you upgrade to a newer version or another browser.


Your browser appears to have cookies disabled. For the best experience of this website, please enable cookies in your browser

We'll assume we have your consent to use cookies, for example so you won't need to log in each time you visit our site.
Learn more

Atypical fracture risk outweighed by bisphosphonates benefit

  • Comment

The risk of atypical fractures from taking bisphosphonates in people with osteoporosis is low, according to US researchers.

Previous reports have raised concerns that long-term treatment of osteoporotic patients with bisphosphonates might cause unusual types of fractures in the hips and thighs.

As a result, US researchers reviewed 12 studies reporting rates of atypical femoral fractures in people receiving bisphosphonates for osteoporosis.

Their findings, presented this week at the American College of Rheumatology annual meeting in Washington, revealed that the atypical fracture risk in bisphosphonate-treated osteoporosis patients was low.

For every 10,000 patients, each treated for a year, only two to 30 developed atypical fractures.

The review authors said: “While atypical fractures associated with bisphosphonates can occur, their incidence is low, and fear of this rare side effect should not outweigh the known significant benefits of bisphosphonates, which have been proven to reduce fractures from weak bones.”

  • Comment

Have your say

You must sign in to make a comment

Please remember that the submission of any material is governed by our Terms and Conditions and by submitting material you confirm your agreement to these Terms and Conditions. Links may be included in your comments but HTML is not permitted.

Related Jobs