The National Institute for Health and Care Excellence has updated its guidance on the diagnosis and management of varicose veins to reflect new treatments and approaches
In this article…
- Overview of the updated NICE guidance on varicose veins
- Discussion of the recommendations
- Explanation of the available treatments
Sarah Onida is a core surgical trainee at North West Thames Rotation, London; Alun H Davies is a professor of vascular surgery at Imperial College London, honorary consultant vascular surgeon at Imperial College Healthcare Trust, London, and chair of the NICE guideline development group for varicose veins.
Onida S, Davies A (2013) Varicose veins: diagnosis and management. Nursing Times; 109: 41, 16-17.
Varicose veins affect up to one-third of the UK population. Many health professionals are therefore likely to come into contact with patients who have venous disease and need to understand how to assess, manage and treat this condition.
This article discusses the updated guidelines from the National Institute for Health and Care Excellence on how health professionals can best treat patients who present with varicose veins.
5 key points
- Varicose veins affect around one-third of the UK population
- Primary varicosities occur when valves between superficial and deep veins are not fully functioning
- Secondary varicosities are caused by venous drainage being reduced by increased pressure or pathology
- Patients with varicose veins are at increased risk of developing deep venous thrombosis
- Open surgery is being replaced by less invasive techniques to treat varicose veins
Varicose veins are visible, dilated, tortuous veins that can appear anywhere in the body where there is poor venous return, and are most often found in the lower limbs. They are a common complaint, affecting up to one third of the UK population and are a significant cause of morbidity (Evans et al, 1999).
Varicose veins can cause a variety of symptoms ranging from itching to ulceration; they have a negative impact on quality of life and are thought to be associated with depression (Sritharan et al, 2012).
The National Institute for Health and Care Excellence has issued an updated guideline on the treatment of varicose veins in adults (NICE, 2013).
Although their exact cause is not clear, varicose veins are classified as primary or secondary.
Primary varicosities are a result of poor venous drainage from the superficial into the deep system. Superficial veins drain into deep veins at specific anatomical locations; two important sites are the groin and the back of the knee, known as the saphenofemoral and saphenopopliteal junctions, which are controlled by valves. When these valves are damaged or not fully functioning, drainage from the superficial system is poor, which leads to increased venous pressure and the development of varicosities.
Secondary varicosities occur from underlying pathology that reduces venous drainage, including deep venous thrombosis (DVT), deep venous incompetence and increased pressure caused by an intra-abdominal mass or obesity; they are also associated with pregnancy.
Varicose veins are a manifestation of long-term venous disease, which can present in a number of ways.
Patients most commonly complain of itching, swelling, aching, restless legs and cramps. Symptoms tend to be worse at the end of the day or after long periods spent standing or sitting.
In severe cases, the increased venous pressure in the legs can lead to changes in the skin. These include eczema, staining (haemosiderin deposition), thickening (lipodermatosclerosis) and, ultimately, ulceration. Patients who have varicose veins also have a higher risk of developing DVT.
Venous duplex or ultrasound scans are the optimal imaging modalities for the venous system. These non-invasive techniques can assess how well the superficial and deep venous systems are working.
A duplex ultrasound should be used to confirm the diagnosis of varicose veins and the extent of truncal reflux, and to plan treatment for patients with suspected primary or recurrent varicose veins.
The guideline highlights the importance of using a patient-centred approach to empower people with varicose veins to make informed decisions about their care. It says they should be given information explaining what varicose veins are and their possible causes. The discussion should include:
- The likelihood of progression and possible complications, including DVT, skin changes, leg ulcers, bleeding and thrombophlebitis, and any misconceptions the patient may have about complications;
- Treatment options, including symptom relief, an overview of interventions and their risks and benefits, and the role of compression;
- Advice on weight loss and physical activity, what may worsen symptoms and when and where to seek further medical help.
Unlike previous guidance, the updated guideline focuses on alleviating symptoms and preventing the most severe consequences of venous disease, such as ulceration.
The first-line treatment for patients with confirmed varicose veins and truncal reflux is endothermal ablation of the long saphenous vein. This uses heat energy to burn the vein from the inside under local anaesthesia; the heat can be delivered via radiofrequency or laser energy.
A catheter is inserted into the vein under ultrasound guidance, and treatment is delivered through this. If endothermal ablation is not suitable, ultrasound-guided foam sclerotherapy should be offered instead. If neither option is suitable, surgery should be offered.
Both radiofrequency and endovenous laser ablation have been shown to be as effective as open surgery and have similar recurrence rates; however, endovenous ablation has a quicker recovery time and higher quality-of-life scores (Rasmussen et al, 2011; Brar et al, 2010). Endothermal ablation is only effective in veins large enough to accommodate the catheter; in smaller veins, foam sclerotherapy is recommended. This involves injection of a chemical sclerosant into the vein and applying pressure, allowing it to scar from within.
If interventional treatments are unsuitable, graded compression therapy can be used. This works by compressing the superficial venous system, promoting drainage in the deep veins. The guideline states that stockings should not be used for more than seven days, or used as a first-line treatment unless no other intervention is suitable.
Management during pregnancy
Pregnancy can exacerbate the symptoms of existing varicose veins, cause new ones to develop and increase the risk of venous thromboembolism. Intervention on the venous system carries a risk of DVT of 0.5-1% (Marsh et al, 2010) so should be avoided during pregnancy unless absolutely necessary. Compression therapy is a useful alternative.
Pregnant women should be given specific information about varicose veins and pregnancy. No interventional treatments should be carried out unless these are absolutely necessary; compression hosiery should be used to relieve leg swelling associated with varicose veins.
Some patients may require referral to a vascular service (Box 1). Bleeding varicose veins may be a life-threatening emergency that need immediate medical attention (Fragkouli et al, 2012).
Referral is also warranted for patients with symptomatic varicose veins or skin changes.
All members of the healthcare team need a good understanding of the underlying causes of venous disease and its management so they can give patients who have varicose veins up-to-date, accurate information; those involved in managing these patients need to be familiar with the updated guideline.
Patient education is paramount, particularly with the recent shift from open to endovascular techniques. Risks, benefits and treatment options need to be considered and discussed with patients to ensure the most appropriate treatment is provided.
The full NICE guideline can be found at: www.nice.org.uk/cg168
Brar R et al (2010) Surgical management of varicose veins: a meta-analysis. Vascular; 98: 1117-1123.
Evans CJ et al (1999) Prevalence of varicose veins and chronic venous insufficiency in men and women in the general population: Edinburgh Vein Study. Journal of Epidemiology and Community Health; 53, 149-153.
Fragkouli K et al (2012) Unusual death due to a bleeding from a varicose vein: a case report. BMC Research Notes; 5, 488.
Marsh P et al (2010) Deep vein thrombosis (DVT) after venous thermoablation techniques: rates of endovenous heat-induced thrombosis (EHIT) and classical DVT after radiofrequency and endovenous laser ablation in a single centre. European Journal of Vascular and Endovascular Surgery; 40: 4, 521-527.
National Institute for Health and Care Excellence (2013) Varicose Veins in the Legs: the Diagnosis and Management of Varicose Veins. London: NICE.
Rasmussen LH et al (2011) Randomised clinical trial comparing endovenous laser ablation, radiofrequency ablation, foam sclerotherapy and surgical stripping for great saphenous varicose veins. British Journal of Surgery; 98: 1079-1087.
Sritharan K et al (2012) The burden on depression in patients with symptomatic varicose veins. European Journal of Vascular and Endovascular Surgery; 43: 4, 480-48