Osteoporosis treatment triples risk of bone necrosis
According to the Canadian research conducted on more than 87,837 patients, those on oral bisphosphonates were 2.87 times more likely to develop bone necrosis.
Bone necrosis is a condition where blood supply is cut off, causing the internal tissues of the bone to collapse and die.
The US Food and Drug Administration issued a warning at the beginning of the month that oral bisphosphonates can cause severe bone pain.
Journal of Rheumatology (2008) Online First
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