Your browser is no longer supported

For the best possible experience using our website we recommend you upgrade to a newer version or another browser.

Your browser appears to have cookies disabled. For the best experience of this website, please enable cookies in your browser

We'll assume we have your consent to use cookies, for example so you won't need to log in each time you visit our site.
Learn more

Brain injured children and cooling

  • Comment
Hypothermia therapy does not improve the neurologic outcome and may increase mortality in children with severe traumatic brain injury, warn Canadian researchers.

They randomly assigned 225 children with severe traumatic brain injury to either hypothermia therapy (32.5°C for 24 hours) initiated within eight hours after injury or to normothermia (37.0°C). They measured the proportion of children who had an unfavourable outcome, such as severe disability, persistent vegetative state, or death six months later.

After follow-up, they found 31% of the patients in the hypothermia group, as compared with 22% of the patients in the normothermia group, had an unfavourable outcome. This included 23 deaths in the hypothermia group and 14 deaths in the normothermia group.

Lengths of stay in the intensive care unit and in the hospital and other adverse events were similar in the two groups, the authors added.

New England Journal of Medicine (2008) 358: 2447-2456

  • Comment

Have your say

You must sign in to make a comment

Please remember that the submission of any material is governed by our Terms and Conditions and by submitting material you confirm your agreement to these Terms and Conditions. Links may be included in your comments but HTML is not permitted.

Related Jobs