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Candida more responsive to single drug

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Yeast infections caused by candidemia respond better to single-drug antifungal prophylaxis (SAP) than a multi-drug regimen of selective digestive tract decontamination (SDD), say Dutch researchers

In 33 studies involving 5,500 patients incidence of candidemia was reduced by SAP but not SDD.
In-hospital mortality was reduced predominantly by SDD.
‘Systemic drugs may be advised as prophylaxis in patients with a high risk of developing candida bloodstream infections, whereas SDD may be given to critically ill patients,’ they said.

Critical Care (2007) 11: R126

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