Obese diabetic children who are resistant to insulin are three times more likely to develop aetherothrombosis than those who are a healthy weight, according to research.
A study involving 313 obese children and adolescents found several factors linked to obesity that increased their likelihood of developing thromboses.
However, when found in insulin-resistant children, the levels of plasminogen activator inhibitor-1 (PAI-1) antigen and von Willebrand factor (vWF) antigen were found to triple this risk.
PAI-1 plays a part in preventing blood clots being broken down by the body, while vWF is a blood glycoprotein involved in haemostasis.
The Greek researchers suggested a link between this impaired prothrombotic state and an increased risk of developing cardiovascular disease in adulthood.