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COPD patients requiring ventilation method transition are 'at higher risk'

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Chronic obstrictive pulmonary disease (COPD) patients who require transition from non-invasive positive-pressure ventilation (NIPPV) to invasive mechanical ventilation (IMV) are at a higher risk of mortality according to US researchers.

NIPPV has helped cut mortality rates in patients hospitalised with COPD, but this small group requiring subsequent treatment with IMV have a significantly higher risk of death than those placed directly on IMV according to US researchers in the American Journal of Respiratory and Critical Care Medicine.

Researchers studied data on 7.5 million COPD admissions over 10 years from 1998-2008.

They stated that the “rising mortality rate in a small but expanding group of patients requiring IMV after treatment with non-invasive ventilation needs further investigation”.

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