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Compound alginate preparations

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VOL: 102, ISSUE: 20, PAGE NO: 36

PROPRIETARY NAMES

 

PROPRIETARY NAMES
- Acidex.

 

 

- Algicon.

 

 

- Gastrocote.

 

 

- Gaviscon.

 

 

- Gaviscon Advance.

 

 

- Gaviscon Infant.

 

 

- Peptac.

 

 

- Rennie Duo.

 

 

- Topal.

 

 

- A number of over-the-counter products are also available.

 

 

ACTION
- Antacids that contain alginates form a raft floating on the surface of the stomach content and therefore reduce reflux and protect the oesophageal mucosa.

 

 

CLASSIFICATION
- Dyspepsia and gastro-oesophageal reflux disease.

 

 

- Compound alginates and proprietary indigestion preparations.

 

 

INDICATIONS
- Management of mild symptoms of oesophageal reflux.

 

 

CONTRAINDICATIONS
- Hypersensitivity to any of the preparation’s ingredients.

 

 

CAUTIONS
- Salt-restricted diets.

 

 

SIDE-EFFECTS
- Stomach distension.

 

 

- Nausea.

 

 

INTERACTIONS
- Taking these preparations at the same time as other medication may impair the medication’s absorption or damage its enteric coating.

 

 

ADMINISTRATION
- Tablets.

 

 

- Suspension.

 

 

- Liquid.

 

 

- Oral powder.

 

 

NURSING CONSIDERATIONS
- Some preparations may have a high sugar content and are therefore not suitable for those with diabetes.

 

 

- Gastro-oesophageal reflux in infants is common and mostly resolves at 12-18 months. Before treatment with alginates is considered, management by changing posture and thickening feeds should be tried.

 

 

- The additional ingredients in these preparations varies considerably, so products should not be regarded as freely interchangeable.

 

 

- Liquid antacids have the advantage of very rapid onset of action and are often perceived to work more quickly. However, a comparison of the speed of tablet versus liquid antacids has not been clinically evaluated.

 

 

PATIENT TEACHING
- Advice should be given about making lifestyle changes such as avoiding excess alcohol, weight loss, smoking cessation and raising the end of the bed.

 

 

- It is safe to stop alginate preparations as soon as symptoms have improved.

 

 

- Patients should feel the benefit of an alginate preparation in 10-20 minutes of taking it and the effect should last for around 3-4 hours.

 

 

- Tablet preparations need to be chewed rather than sucked to allow the raft-forming mechanism to work effectively.

 

 

- Advise patients that they can eat or drink as soon as reflux symptoms subside. However, this will lessen the benefit of the preparation as the reflux-preventing raft will be broken.

 

 

Nurses should refer to manufacturer’s summary of product characteristics and to appropriate local guidelines

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