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Cancer survivor woman patient chemotherapy

Revised advice on use of imatinib for chronic myeloid leukaemia

Chronic myeloid leukaemia (CML) is a chronic, clonal, myeloproliferative disorder that is typically triphasic. There is a prolonged chronic phase (three to six years), followed in most cases by an accelerated phase (three to 12 months) during which there is disease progression, and finally an aggressive, almost always terminal, blast phase (sometimes called blast crisis). Progression from chronic phase to accelerated or blast phase is termed transformation. Patients may present in accelerated ..

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