Anaphylactic shock following vaccination is “extremely rare,” according to research by University Hospital Southampton NHS Foundation Trust, published online in the Archives of Disease in Childhood.
During one year the authors found 15 cases of suspected anaphylaxis after vaccination were reported in children under 16 in the UK and Ireland.
Only seven of these cases were confirmed as anaphylaxis. The majority involved either HPV vaccine or single component measles vaccine.
Two of the cases were associated with the single component measles vaccine. As more than 16,000 doses were imported over the study period, this gives an incidence of 12 cases of anaphylaxis for every 100,000 doses, said the authors.
Three of the cases were associated with the HPV vaccine. More than two million doses of this vaccine were administered during the study period, giving an incidence of 1.4 cases per million doses.
None of the cases were associated with the normal pre-school or infant immunisation schedule, including the triple MMR jab.
“This is extremely reassuring data for the general public and healthcare workers alike,” the authors added.