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Sickle cell anaemia: causes, signs, symptoms and treatment

Sickle cell disorders are a group of inherited conditions that affect the red blood cells (erythrocytes). They include sickle cell anaemia, haemoglobin sickle cell disease and beta thalassaemia. Of these the most common and severe is sickle cell anaemia. It is a global health problem, affecting many races and ethnic groups. The World Health Organization estimates that more than 250,000 babies are born each year with the disorder (WHO, 1989).

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