Respiratory symptoms vary significantly during different stages of the menstrual cycle, with higher frequencies during the mid-luteal to mid-follicular stages, according to a Norwegian study.
A total of 3,926 women with regular cycles who were not taking exogenous sex hormones were surveyed by researchers from Haukeland University Hospital.
Reported wheezing was higher on cycle days 10-22, with a mid-cycle dip near the putative time of ovulation. Shortness of breath was highest on days 7-21, with a dip just prior to mid-cycle. The incidence of cough was higher just after putative ovulation in those with asthma.
Lead author Ferenc Macsali said: “Our results point to the potential for individualising therapy for respiratory diseases according to individual symptom patterns. Adjusting asthma medication, for example, according to a woman’s menstrual cycle might improve its efficacy.”
The findings were due to be published online in American Journal of Respiratory and Critical Care Medicine.