Health officials say it is only a matter of time before the measles outbreak in Wales claims its first life.
More than 200 cases are being investigated by the National Public Health Service for Wales (NPHS). Both parents and children remain at risk of developing measles if they are overdue their MMR injection, the NPHS warned.
Dr Marion Lyons, head of the health protection teams, said it was only a matter of time before someone died or was permanently affected by the virus.
The majority of cases came in mid and west Wales, with 147 people affected, including 23 who were admitted to hospital. There were 53 cases in Llandudno, north Wales, with two people admitted to hospital, and seven in the south east, with one person needing hospital treatment.
Four measles outbreaks in South Pembrokeshire, Llanelli, Burry Port and Neath Port Talbot have been linked to at least 89 cases in mid and west Wales.
Outbreaks at two schools - Ysgol Ffordd Dyffryn and Ysgol John Bright - were found to be the likely cause of cases in the north.
While some cases in south-east Wales have been sporadic, five have family ties to outbreaks in mid and west Wales.