Your browser is no longer supported

For the best possible experience using our website we recommend you upgrade to a newer version or another browser.

Your browser appears to have cookies disabled. For the best experience of this website, please enable cookies in your browser

We'll assume we have your consent to use cookies, for example so you won't need to log in each time you visit our site.
Learn more

Experimental drug shown to benefit lifestyle of patients with MS

  • Comment
An experimental drug has been shown in trials to benefit the lifestyle of patients with MS, according to US researchers.

People with MS felt better, walked faster and had better leg strength after using the drug fampridine compared to those on placebo, a small study has shown.

Clinicians gave 301 patients aged 18-70 with all course types of the neurodegenerative disease either 10mg fampridine twice daily or placebo for 14 weeks.

When assessed at two weeks then every four weeks, those on active treatment had a faster walking speed in three of the four assessments compared with the fastest when not on treatment to those just taking sugar pills (78/224 or 35% compared to 6/72 or 8%).

This group also had greater improvement in leg strength and on all 12 items in the multiple sclerosis walking scale.

Two serious adverse events – focal seizure and severe anxiety – were associated with use of fampridine in this study. Other research has shown that risk of seizure increases in a dose-dependent way with fampridine.

Lancet (2009) 373: 732–38

  • Comment

Have your say

You must sign in to make a comment

Please remember that the submission of any material is governed by our Terms and Conditions and by submitting material you confirm your agreement to these Terms and Conditions. Links may be included in your comments but HTML is not permitted.