Serum testosterone and estradiol levels were measured and the occurrence of a low-trauma fracture was determined during follow up.
Low-trauma fractures occurred in 113 men. Those with low blood testosterone levels were 33% more likely to suffer from a fracture.
Authors write: ‘While testosterone may affect fracture risk via skeletal and non-skeletal mechanisms, the present findings suggest that measurement of serum testosterone provides additional clinical information for the assessment of fracture risk in elderly men.’
Archives of Internal Medicine (2008) 168:47-54