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Glucose key in renal protection

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Intensive glucose control in type 2 diabetes can significantly reduce the risk of kidney damage, according to international researchers.

They studied 11,140 patients, of whom half received intensive glucose control – using a modified release version of a sulfonylurea gliclazide to achieve an HbA1c of 6.5% – and the rest received standard control.

After five years, the intensive group were 21% less likely to suffer from new or worsening nephropathy compared with the control group, whose average HbA1c was 7.3%.

‘The clear reduction in nephropathy is important because indexes of renal impairment are strongly associated with the future risk of major vascular events,’ the authors said online in the New England Journal of Medicine.

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