This 32 year-old male presented with a non-blanching rash across his lower extremities, hands, and the mucosal surfaces of his mouth.
He had no significant past medical history, no recent sexual activity or travel, and his CBC showed no abnormalities. Do you think this is hand-foot-and-mouth disease or something more severe?
Answer: Hand-foot-and-mouth disease (HFMD) is related to herpangina, another syndrome caused by the same set of viruses. Both herpangina and HFMD are caused by enteroviruses, most commonly Coxsackievirus A.
See more cases like this at Figure 1