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Lack of evidence on benefit of 'ultra-low' cholesterol

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There is no evidence to support an 'ultra-low' LDL-cholesterol target for people at high risk of heart disease, according to a review of research by US authors.

There is no evidence to support an 'ultra-low' LDL-cholesterol target for people at high risk of heart disease, according to a review of research by US authors.

The researchers from the University of Michigan Health Systemfound that there is no scientifically valid evidence to support pushingLDL cholesterolas a low as 70 mg/d.

It may be wiser to concentrate on getting more people with multiple heart disease factors on statin drugs regardless of their cholesterol levels rather than on pushing high-risk patients cholsterol levels as low as possible with multiple drugs, they concluded.

Annals of Internal Medicine(2006) 145:520-530

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