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MS patients treated with own stem cells

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MS patients treated with their own bone marrow stem cells have shown “encouraging” progress, a study claims.

In the trial, University of Bristol researchers harvested bone marrow while volunteers were under general anaesthetic, preparing them for injecting into the patients’ veins a few hours later.

Study leader Professor Neil Scolding said the results offer “tantalising” potential after the six participants, aged between 30 and 60, tolerated the procedure well.

The results of the test scores were suggestive of “stable disease”, the team found.

The study is one of the first to treat MS with a patients’ own bone marrow stem cells.

Prof Scolding, Burden Professor of Clinical Neurosciences, said: “We are encouraged by the results of this early study. We believe that stem cells mobilised from the marrow to the blood are responsible, and that they help improve disease in several ways, including neuroprotection and immune modulation.”

A full report on the trial is published online in Clinical Pharmacology and Therapeutics.

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