The long-acting insulin NPH is as effective in treating type 2 diabetes as newer, more expensivekinds of insulin, such as glargine or detemir, according to a Cochrane review.
Researchers looked at eight studies of between 24 and 52 weeks, involving 2,293 patients. They found that insulin glargine or insulin detemir were almost identical to NPH in lowering levels of HbA1c.
The newer insulins, however, caused fewer problems with low blood glucose while patients were sleeping.
Cochrane Database of Systematic Reviews (2007) 2