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Nitric oxide has 'little effect' on preterm survival rates

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The administration of nitric oxide to preterm infants to reduce rates of poor lung development (bronchopulmonary dysplasia) and improve survival in these children appears to have little effect, according to European researchers.

Their study, published online in The Lancet, involved 800 preterm infants from nine countries, who were randomised to inhaled nitric oxide (five parts per million) or placebo gas (nitrogen gas) for a minimum of seven days and a maximum of 21 days.

They found giving nitric oxide to these babies did not improve overall survival or their survival without poor lung development or brain injury.

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