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Sugar solution reduces jab pain in older infants

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A sugar solution can have a calming and pain relieving effect in infants over the age of one year during vaccination, according to researchers.

The Norwegian study sought to investigate the effect of 30% sucrose compared with a placebo as pain relief and comfort during immunisation of 15-month-old children.

“Public health nurses should use a 30% sucrose solution for pain relief during immunisation of 15-month-old infants”

Study authors

The study authors noted that sweet solutions function as pain relief during immunisation for infants up to the age of one year, but said there had been few previous studies of older children.

In their study, around 15-month-old infants were randomly assigned to an intervention group that received a 30% sugar solution or a control group that received a placebo.

The study was performed at three healthcare centres, with duration of crying as the outcome measure. A total of 114 children took part.

The intervention group infants’ crying was significantly shorter – lasting on average 18 second –compared with the control group infants – 33 seconds mean – said the study authors.

“This trial revealed that 30% sucrose orally has a calming and pain-relieving effect on 15-month-old infants during immunisation,” they said in the Journal of Clinical Nursing.

“Public health nurses should use a 30% sucrose solution for pain relief during immunisation of 15-month-old infants,” they added.

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