Researchers divided subjects into five groups according to serum hormone levels and calculated risk of prostate cancer occurring.
They found no statistical likelihood of those with high serum concentrations of testosterone, dihydrotestosterone, dehydroepiandrosterone sulfate, androstenedione,
androstanediol glucuronide, and estradiol and prostate cancer.
Authors write: 'The study obliges the scientific community to move past a seductive, clinically relevant, and biologically plausible hypothesis and get on with the difficult task of exploring, analyzing, and characterizing modifiable risk factors for prostate cancer.'
Journal of the National Cancer Institute (2008) 100: 170-183