VOL: 102, ISSUE: 13, PAGE NO: 35
Generic and proprietary names
There are also several products that contain nystatin in combination with other agents.
- An antifungal drug named after the New York State Institute of Health, where it was developed in the 1950s.
- It interferes with fungal DNA replication.
- Candidal fungal skin infections.
- Oral and perioral candidal fungal infections.
- Candidal fungal vaginal infections.
- Diarrhoea at high oral doses.
- Local irritation.
- Local sensitisation.
- Stevens-Johnson syndrome.
- Oral suspension.
- Lozenge (pastille).
- Vaginal pessary.
- Vaginal cream.
- Topical ointment.
- Topical cream.
- Recurrent vaginal infection can be associated with courses of antibacterial medication, diabetes, pregnancy, oral contraception and reinfection from a sexual partner.
- Good oral hygiene, including proper care of dentures, is important for the cure of mouth infections.
- Evaluate therapeutic response.
- Warn women using vaginal preparations that this medication can stain clothing yellow and that they should avoid using tampons because they will absorb the drug.
- Advise patients to continue to use nystatin lozenges for at least 48 hours after symptoms of infection disappear.
- Lozenges should be allowed to dissolve slowly in the mouth and not chewed or swallowed whole.
- Advise patients using nystatin suspension to shake the bottle well before each use to mix the medication evenly.
- For mouth infections half the dose should be placed in each side of the mouth and swished throughout the mouth for several minutes before swallowing.
- For intestinal infections the suspension can simply be swallowed.
- Advise patients using nystatin skin ointment or cream that it should be kept out of the eyes.
- For cream and ointment application a small amount should be gently and thoroughly massaged into the skin.
Nurses should refer to manufacturer’s summary of product characteristics and to appropriate local guidelines