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Osteoporosis treatment triples risk of bone necrosis

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Drugs commonly used in the treatment of osteoporosis nearly triple the risk of bone necrosis, according to a study.
According to the Canadian research conducted on more than 87,837 patients, those on oral bisphosphonates were 2.87 times more likely to develop bone necrosis.

Bone necrosis is a condition where blood supply is cut off, causing the internal tissues of the bone to collapse and die.

The US Food and Drug Administration issued a warning at the beginning of the month that oral bisphosphonates can cause severe bone pain.


Journal of Rheumatology (2008) Online First

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