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Patients stop taking OAB drugs because of perceived lack of efficacy

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Nine out of ten patients who discontinue taking medication for overactive bladder do so because they say it does not work as expected or they could not tolerate it, according to research published online in the British Journal of Urology International.

US researchers surveyed 6,577 adults who had been prescribed medication for overactive bladder in the last 12 months.

A quarter of respondents had discontinued one or more of their drugs in the last year, with the majority giving multiple reasons for doing so.

Just under half said it was because the medication did not work as expected, 23 per cent because they learnt to get by without medication and 21 per cent because of side effects.

Other reasons included cost, change of insurance status, not wanting to use medication, advice from health professionals and health improvements.

The authors, from Loyola University in Chicago, said: “Encouraging people with long-term health conditions to persist with medication is common and problematic.

“Recent database studies suggest that the number of OAB patients who stop taking their medication is much higher than clinical trials would suggest.

“It is important to identify why people stop taking their medication as persistence with medication is generally associated with positive health outcomes and reductions in healthcare resource use and costs.”


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