Your browser is no longer supported

For the best possible experience using our website we recommend you upgrade to a newer version or another browser.

Your browser appears to have cookies disabled. For the best experience of this website, please enable cookies in your browser

We'll assume we have your consent to use cookies, for example so you won't need to log in each time you visit our site.
Learn more

Question mark over efficacy of fertility treatments

  • Comment
Long-established interventions to help couples with fertility problems have limited efficacy, according to an Aberdeen University study.

Researchers compared no intervention with oral clomifene citrate (CC) and unstimulated intra-uterine insemination (IUI). The randomised trial involved 580 women who had experienced unexplained infertility for more than two years from five hospitals in Scotland.

Overall, 101 women became pregnant and had a live birth during the study. Researchers found women who had no interventions had a live birth rate of 17%, compared with 14% for CC and 23% for IUI. This difference was not statistically significant, the authors said.

‘These interventions, which have been in use for many years, are unlikely to be more effective than no treatment. These results challenge current practice, as endorsed by a national guideline in the UK,’ the authors said in the BMJ online.

‘As a direct result of the lack of evidence, many couples with unexplained infertility endure (and even request) expensive, potentially hazardous, and often unnecessary treatments,’ warned Tarek El-Toukhy and Yacoub Khalaf from the assisted conception unit at Guy’s and St Thomas’ NHS Foundation Trust, London, in an accompanying editorial.

  • Comment

Have your say

You must sign in to make a comment

Please remember that the submission of any material is governed by our Terms and Conditions and by submitting material you confirm your agreement to these Terms and Conditions. Links may be included in your comments but HTML is not permitted.

Related Jobs