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'Vaccine cost system lets harm from meningitis B continue'


Emmeline McArdle, a nurse from Kent, knows only too well the devastation that meningococcal B meningitis (MenB) and septicaemia cause.

Her sister Jolene was just 19 when she woke in the early hours of the morning complaining of aching joints and flu-like symptoms. A little over 24 hours later, Jolene was dead, leaving behind a family that 12 years on still feel the loss.

MenB infection can kill a healthy child within hours of the first symptoms appearing and will leave one-third of survivors with life-altering after effects that can be as severe as brain damage, deafness and amputations.

A vaccine that protects against MenB was licensed in January 2013 but, in June of the same year, the UK’s Joint Committee on Vaccination and Immunisation, which makes recommendations on what vaccines the government should make available, said MenB vaccination was unlikely to be cost effective.

Our response as a charity that knows only too well the devastating personal consequences and wider costs of this disease was to highlight the areas we thought had been undervalued.

For example, the diversity of disabling after-effects are hard to capture and were not fully represented, nor were the wider health impacts on carers. Our full response can be read at

As the debate continues, it has become clear that, although it is important for all the relevant costs to be considered, it is the underlying methodology of the cost effectiveness analysis (CEA) that is making it harder for vaccines that protect children against rare but severe illness to make the cut.

There is evidence that the public prefer preventive interventions over cures, and would rather prevent death or severe disability in a few than mild illness among the masses. However, CEA does not reflect these preferences. Children are at a disadvantage because much higher importance is placed on immediate health gains compared with those that are sustained far into the future.

To put this into context, CEA values the overall health loss associated with 5,400 cases of uncomplicated influenza to be the same as the death of a three-month-old child with an average UK life expectancy (80 years). Add to this the fact that the tool currently used cannot adequately measure health loss in children, then it seems that the MenB vaccine and future childhood vaccines for rare, severe illnesses will face an uphill struggle.

We submitted our reservations to the JCVI about the fairness of the cost-effectiveness model before they reconvened in February 2014.

While we wait for their decision, we continue our campaign for the introduction of safe and effective meningitis


● The Meningitis Research Foundation is backing a letter to the health secretary from doctors, nurses and scientists. Visit to join us in the fight against meningitis.

Claire Wright is medical information officer, Meningitis Research Foundation


Readers' comments (5)

  • tinkerbell

    An ounce of prevention is worth a ton of cure for such a life threatening condition.

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  • My son in law had bacterial meningitis as a child which nearly rendered him blind. He now wears very thick glasses, and continues to suffer problems related to the disease.

    Yet day after day I see in A&E people pouring in for attention to long term conditions and minor problems because it is more convenient for them to turn up there rather than make a routine appointment at GP surgeries, or because they want everything "now.".

    The 111 waste of time service sends out ambulances willy nilly to people with simple, non urgent problems. GP out of hours are used now merely as a convenience rather than conditions that cannot possibly wait until GP surgeries open in the morning. GP surgeries have many unattended appointments weekly.

    Its about time these time wasters and inappropriate attenders were fined/charged. Maybe the money then could be re-directed to more important things like the Meningitis B vaccine.

    We could cut down on ridiculously high attendances - many shifts I don't really think I have done anything worthwhile due to the minor problems that are considered "urgent" or "emergency" by over demanding "patients."

    And have more money to spend on what really matters. Double whammy.

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  • 111 seems to have added to the problems rather than helping to solve them.

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  • "Its about time these time wasters and inappropriate attenders were fined/charged." Anonymous | 11-Mar-2014 10:58 am

    not sure how you decide and discriminate. many considered to be time wasters turn out to be serious cases which are overlooked as in the case of a very dear and highly respected colleague on my ward, turned away from A&E one evening and dead within 24hours of her return the following morning and urgent admission to hospital.

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  • Anonymous | 11-Mar-2014 2:27 pm

    not very helpful for patients who are really in need. consulting a GP is hardly an optional luxury much of the time!

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