A bail application for a 27-year-old nurse charged with contaminating saline at a hospital has been refused.
Rebecca Leighton was arrested last month by detectives investigating the deaths of patients at Stepping Hill Hospital in Stockport, Greater Manchester.
She is accused of three counts of criminal damage with intent to endanger life and three counts of being reckless as to whether life was being endangered.
The charges relate to the alleged tampering with of saline ampoules, saline bags and medical products.
Leighton, who is currently on remand at Styal Prison, did not appear at Manchester Crown Court for the hearing.
Mr Justice Henriques ruled that Leighton should be kept in custody for her own protection.
She is next due to appear in court on 17 October for a plea and case management hearing.
A provisional trial date of 28 February next year has been set.
Leighton, of Buxton Road, Heaviley, is also charged with theft of medicines.