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Side-effects lead patients to stop taking antimuscarinic medications

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Patients expectations about the effect of treatment and their experience of side effects are the main reasons for stopping antimuscarinic therapy use in the treatment of over active bladder symptoms.

US researchers surveyed 5,392 patients who took one or more medication for treatment of overactive bladder.

Of these, 24.5% reported that they discontinued one or more antimuscarinic drugs during the previous 12 months. The majority of patients said that treatment did not match up to their expectations and/or they had problems with side effects.  

The authors recommend that interventions are developed to promote realistic expectations about treatment and the risk of side effects.

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