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Antidepressants of 'no benefit' to children

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Antidepressants commonly prescribed to adults with autistic spectrum disorders should not be prescribed to children, according to a Cochrane review.

Despite some evidence of benefits in adults with autism, the authors said there was no evidence for any benefits associated with selective serotonin reuptake inhibitors (SSRIs) in children, who may suffer serious adverse effects as a result of taking the drugs.

They reviewed seven trials, which involved 271 patients and evaluated the drugs fluoxetine, fluvoxamine, fenfluramine and citalopram.

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