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Antibiotic-based lock solutions not recommended for CRBSI prevention

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New research suggests that antibiotic-based lock solutions are not effective at preventing catheter-related bloodstream infections (CRBSI)

The research, published in the Journal of Hospital Infection, assessed the efficacy of antibiotic-based lock solutions to prevent CRBSI in haemodialysis, oncology patients and newborns.

The study found indications that antibiotic-based lock solutions are effective in the prevention of CRBSI in haemodialysis patients, although in trials studying oncology patients the effect showed only a marginal significant benefit in favour of antibiotic-based lock solutions.

The review authors are not recommending routine use of antibiotic-based catheter lock solutions.

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