Records of 2,780 children with bacterial meningitis admitted to 27 hospitals were analysed – 10% received corticosteroids.
Mortality rates were 6% among children given corticosteroids versus 4% for those not given them.
Time to discharge did not differ significantly.
‘Adults may have different predisposing factors for meningitis or a different inflammatory response, either of which may alter the course of disease compared to children,’ suggest the authors.
Journal of the American Medical Association (2008) 299: 2048–2055