A recent study published in the journal Thorax has suggested that high-intensity non-invasive positive pressure ventilation (NPPV) is more effective at controlling nocturnal hypoventilation in COPD patients than conventional low-intensity NPPV.
The study aimed to determine whether the the novel approach of high-intensity NPPV is more effective than the conventional low-intensity NPPV at controlling nocturnal hypoventilation in patients with stable hypercapnic COPD.
The trial looked at 6 weeks of high-intensity NPPV performed in 17 patients with severe stable hypercapnic COPD.
The results showed that high-intensity NPPV is better tolerated by patients with severe chronic hypercapnic COPD and is superior to the conventional and widely-used form of low-intensity NPPV in controlling nocturnal hypoventilation. High-intensity NPPV therefore offers a new promising therapeutic option for these patients.