Your browser is no longer supported

For the best possible experience using our website we recommend you upgrade to a newer version or another browser.

Your browser appears to have cookies disabled. For the best experience of this website, please enable cookies in your browser

We'll assume we have your consent to use cookies, for example so you won't need to log in each time you visit our site.
Learn more

Taking Prozac while pregnant may increase risk of birth defects

  • Comment
Pregnant women who take the antidepressants fluoxetine (Prozac) and paroxetine (Seroxat) have an increased risk of giving birth to babies with heart anomalies, warn international researchers.

They studied 2,191 women – 410 who had taken paroxetine (Seroxat) during pregnancy, 314 who had taken fluoxetine (Prozac) and 1,467 controls who had not taken an antidepressant.

Those taking fluoxetine (Prozac) during the first three months of pregnancy gave birth to four times as many babies with heart problems as women who did not, while those taking paroxetine (Seroxat) gave birth to three times more children with anomalies than controls, said the researchers from Israel, Italy and Germany.

‘It’s estimated that as many as one in seven women suffer from clinical depression during pregnancy and clinicians need to weigh up the individual risks of pregnant women taking, or not taking, drugs like fluoxetine (Prozac),’ the authors said.

‘We should point out that there is no evidence of any increased risk posed by citalopram (Cipramil) and sertraline (Lustral), which belong to the same group of antidepressants,’ they added.

British Journal of Clinical Pharmacology (2008) 66: 695-705

  • Comment

Have your say

You must sign in to make a comment

Please remember that the submission of any material is governed by our Terms and Conditions and by submitting material you confirm your agreement to these Terms and Conditions. Links may be included in your comments but HTML is not permitted.

Related Jobs