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Targeted therapies for patients with rheumatoid arthritis

Rheumatoid arthritis (RA) is an auto-immune disease that results in a debilitating inflammatory arthritis with no known cure. The immune system treats the body’s own synovial tissue, which lines the articular surfaces of moveable joints, as foreign and launches an immune response against it. When inflammation persists or fails to respond to treatment, destruction of nearby cartilage, bone, tendons and ligaments can occur, leading to permanent disability.

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