Your browser is no longer supported

For the best possible experience using our website we recommend you upgrade to a newer version or another browser.

Your browser appears to have cookies disabled. For the best experience of this website, please enable cookies in your browser

We'll assume we have your consent to use cookies, for example so you won't need to log in each time you visit our site.
Learn more

Vitamin D 'speeds up' TB treatment

  • Comment

Antibiotic treatment of tuberculosis (TB) can be accelerated by vitamin D, according to a study by scientists at Barts and The London School of Medicine and Dentistry.

Their findings, which were published in The Lancet, give fresh insight into how vitamin D may affect the immune response.

A group of 146 patients with drug-sensitive TB received either four oral doses of 2.5mg of vitamin D, or a placebo in a trial led by Dr Adrian Martineau of the Centre for Health Sciences at Barts and The London School of Medicine and Dentistry. The study, funded by the British Lung Foundation, saw all participants receive standard antibiotic treatment for their condition.

The average time it took for TB to clear from the lungs among all study participants was six weeks for those taking standard therapy alone and five weeks for those taking additional vitamin D. The difference, however, was not large enough to sustain statistical significance.

However, patients who had a particular genetic type of vitamin D receptor were much more responsive to vitamin D than others and cleared TB bacteria from their lungs much more quickly if they received vitamin D along with standard antibiotic treatment.

Lead researcher Dr Adrian Martineau said: “The finding that patients who have a particular type of vitamin D receptor are very responsive to vitamin D is new and gives us insights into how vitamin D can affect the immune response.”

  • Comment

Have your say

You must sign in to make a comment

Please remember that the submission of any material is governed by our Terms and Conditions and by submitting material you confirm your agreement to these Terms and Conditions. Links may be included in your comments but HTML is not permitted.

Related Jobs