Patients receiving a coronary stent should not be given warfarin as an anticoagulant, a study has shown.
A Finnish study of 239 patients found they were 70% more likely to die and 3.4 times more likely to suffer severe bleeding after a year than a control group.
The warfarin was used in combination with a range of drugs -the most common being triple therapy with aspirin and clopidogrel, which was used on 48% of the patients in the study group.
The authors concluded that prognosis is unsatisfactory in warfarin-treated patients, irrespective of the drug combination used and that the aspirin and warfarin combination is inadequate to prevent stent thrombosis.
European Heart Journal (2007) Online publication; DOI: 10.1093/eurheartj/eh1488